At CNPEM we acquired competencies and mastered techniques for the development of biological platforms:

  • Structural and molecular biology: synchrotron-based crystallography, electronic microscopy (including cryo-EM) and bioimaging capabilities,
  • Multiomics, multi metaomic approaches and analytical capabilities: genomics, transcriptomics, metabolomics and proteomics,
  • Synthetic biology: biological engineering, bioinformatics and computational biocatalysis (Molecular Dynamics and Quantum Mechanics).

Research equipment for the development of biological platforms is either available at LNBR or at its sister Laboratories at CNPEM.

Main equipment at LNBR facilities

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High-Throughput Sequencing

Genome sequencing, evaluation of the gene expression of various biological systems

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Capillary Electrophoresis System

Determination of profile of carbohydrates from hydrolysis by glycosidic enzymes

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Mass Spectrometry

Mass spectrometry coupled to liquid and gas chromatography to identify and quantify of metabolites in complex biological samples

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Spectrophotometry

Determination of composition of the secondary structure of macromolecules and investigation of thermostability

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Spectrofluorimeter

Characterization of intrinsic and extrinsic fluorescence, phosphorescence, bio and chemiluminescence of macromolecules

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Dynamic Light Scattering

Determination of the structural homogeneity of molecules in solution

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Automated Bioreactors (up to 20L)

Cultivation and characterization of microorganisms (fungi, bacteria, and yeasts), enzymatic hydrolysis, and alcoholic fermentation and support equipment for microbial propagation and biomolecule analysis (NB-1)

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Physciochemical Equipment

Fractionation and milling systems, chemical synthesis, separation and purification of products, chemical catalysis employing reactors capable of operating in a wide range of pressure/temperature, solvents, and pH

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Pilot Plant

Verification and demonstration, on a semi-industrial scale (300 L) of the robustness and stability of technological biotechnological platforms

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Greenhouse

Controlled environment for biotechnological developments for agriculture

Other equipment at CNPEM

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Sirius - Synchrotron Light Source

Sirius, a nova fonte de luz síncrotron brasileira, é a maior e mais complexa infraestrutura de pesquisa já construída no País.

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RMN

Fractionation and milling systems, chemical synthesis, separation and purification of products, chemical catalysis employing reactors capable of operating in a wide range of pressure/temperature, solvents, and pH

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Cryomicroscopy

Verification and demonstration, on a semi-industrial scale (300 L) of the robustness and stability of technological biotechnological platforms

RESEARCH

Research Divisions

Research Facilities

Research Highlights

Scientific Publications

CONTACT US

General LNBR Inquiries
+55 19 3512-1000
lnbrcomunica@cnpem.br

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